Alpha particles, also called alpha rays or alpha radiation, consist of two and two bound together into a particle identical to the atomic nucleus of a helium-4 atom.
Alpha particles have a net spin of zero. When produced in standard alpha radioactive decay, alpha particles generally have a kinetic energy of about 5 MeV and a velocity in the vicinity of 4% of the speed of light. They are a highly ionizing form of particle radiation, with low penetration depth (stopped by a few centimetres of air, or by the skin).
However, so-called long-range alpha particles from ternary fission are three times as energetic and penetrate three times as far. The helium nuclei that form 10–12% of are also usually of much higher energy than those produced by nuclear decay processes, and thus may be highly penetrating and able to traverse the human body and also many metres of dense solid shielding, depending on their energy. To a lesser extent, this is also true of very high-energy helium nuclei produced by particle accelerators.
Alpha particles are commonly emitted by all of the larger radioactive nuclei such as uranium, thorium, actinium, and radium, as well as the transuranic elements. Unlike other types of decay, alpha decay as a process must have a minimum-size atomic nucleus that can support it. The smallest nuclei that have to date been found to be capable of alpha emission are beryllium-8 and tellurium-104, not counting beta-delayed alpha emission of some lighter elements. The alpha decay sometimes leaves the parent nucleus in an excited state; the emission of a gamma ray then removes the excess energy.
However, the quantum tunnelling effect allows alphas to escape even though they do not have enough energy to overcome the nuclear force. This is allowed by the wave nature of matter, which allows the alpha particle to spend some of its time in a region so far from the nucleus that the potential from the repulsive electromagnetic force has fully compensated for the attraction of the nuclear force. From this point, alpha particles can escape.
The energy of alpha particles emitted varies, with higher energy alpha particles being emitted from larger nuclei, but most alpha particles have energies of between 3 and 7 MeV (megaelectronvolt), corresponding to extremely long and extremely short half-lives of alpha-emitting nuclides, respectively. The energies and ratios are often distinct and can be used to identify specific nuclides as in alpha spectrometry.
With a typical kinetic energy of 5 MeV; the speed of emitted alpha particles is , which is 5% of the speed of light. This energy is a substantial amount of energy for a single particle, but their high mass means alpha particles have a lower speed than any other common type of radiation, e.g. Beta particle, neutrons.N.B. Since gamma rays are electromagnetic (light) they move at the speed of light ( c). Beta particles often move at a large fraction of c, and exceed 60% c whenever their energy is > 64 keV, which it commonly is. Neutron velocity from nuclear reactions ranges from about 6% c for fission to as much as 17% c for fusion.
Because of their charge and large mass, alpha particles are easily absorbed by materials, and they can travel only a few centimetres in air. They can be absorbed by tissue paper or by the outer layers of human skin. They typically penetrate skin about 40 , equivalent to a few cells deep.
In 1899, Rutherford discovered that uranium radiation is a mixture of two types of radiation. He performed an experiment which involved two electrodes separated by 4 cm of air. He placed some uranium on the bottom electrode, and the radiation from the uranium ionized the air between the electrodes, creating a current. Rutherford then placed an aluminium foil (5 micrometers thick) over the uranium and noticed that the current dropped a bit, indicating that the foil was absorbing some of the uranium's radiation. Rutherford placed a few more foils over the uranium and found that, for the first four foils, the current steadily decreased at a geometric rate. However, after the fourth layer of foil over the uranium, the current didn't drop anymore and remained more or less level for up to twelve layers of foil. This result indicated that uranium radiation has two components. Rutherford dubbed one component "alpha radiation" which was fully absorbed by just a few layers of foil, and what was left was a second component that could penetrate many layers of foil, and he dubbed the latter "beta radiation".
In 1900, Marie Curie noticed that the absorption coefficient of alpha rays seemed to increase the thicker the barrier she placed in their path. This suggested that alpha radiation is not a form of light but made of particles that lose kinetic energy as they pass through barriers. In 1902, Rutherford found that he could deflect alpha rays with a magnetic field and an electric field, showing that alpha radiation is composed of electrically charged particles. The direction in which the alpha particles were deflected was the opposite of cathode rays, which showed that they are positively charged.Heilbron (1968), pp. 252-254
In 1906, Rutherford made some more precise measurements of the charge-to-mass ratio of alpha particles. Firstly, he found that the ratio was more or less the same whether the source was radium or actinium, showing that alpha particles are the same regardless of the source. Secondly, he found the charge-to-mass ratio of alpha particles to be half that of the hydrogen ion. Rutherford proposed three explanations: (1) an alpha particle is a hydrogen molecule (H2) with a charge of 1 e; (2) an alpha particle is an atom of helium with a charge of 2 e; (3) an alpha particle is half a helium atom with a charge of 1 e. At that time in history, scientists knew that hydrogen ions have an atomic weight of 1 and a charge of 1 e, and that helium has an atomic weight of 4. Nobody knew exactly how many electrons were in an atom. Protons and neutrons had not yet been discovered. Rutherford decided the second explanation was the most plausible because it is the simplest and sizeable deposits of helium were commonly found underground next to deposits of radioactive elements. His explanation was that as alpha particles are emitted by underground radioactive elements, they become trapped in the rock strata and acquire electrons, becoming helium atoms.
Therefore an alpha particle is essentially a helium atom stripped of two electrons.
In 1909, Ernest Rutherford and Thomas Royds finally proved that alpha particles were indeed helium ions. To do this they collected and purified the gas emitted by radium, a known alpha particle emitter, in a glass tube. An electric spark discharge inside the tube produced light. Subsequent study of the spectrum of this light showed that the gas was helium and thus the alpha particles were indeed the helium ions.
In 1911, Rutherford used alpha particle scattering data to argue that the positive charge of an atom is concentrated in a tiny nucleus. In 1913, Antonius van den Broek suggested that the nuclear charge in an atom, and by extension the number of electrons, is equal to its atomic number. Therefore a helium atom has two electrons, and an alpha particle is essentially a helium nucleus. In 1920, Rutherford deduced the existence of the proton as the source of positive charge in the atom. In 1932, James Chadwick discovered the neutron. Thereafter it was known that an alpha particle is an agglomeration of two protons and two neutrons.
Radium-223 is an alpha emitter that is naturally attracted to the bone because it is a calcium mimetic. Radium-223 (as radium-223 dichloride) can be infused into a cancer patient's veins, after which it migrates to parts of the bone where there is rapid turnover of cells due to the presence of metastasized tumors. Once within the bone, Ra-223 emits alpha radiation that can destroy tumor cells within a 100-micron distance. This approach has been in use since 2013 to treat prostate cancer which has metastasized to the bone. Radionuclides infused into the circulation are able to reach sites that are accessible to blood vessels. This means, however, that the interior of a large tumor that is not vascularized (i.e. is not well penetrated by blood vessels) may not be effectively eradicated by the radioactivity.
Radium-224 is a radioactive atom that is utilized as a source of alpha radiation in a cancer treatment device called DaRT (diffusing alpha emitters radiation therapy). Each radium-224 atom undergoes a decay process producing 6 daughter atoms. During this process, 4 alpha particles are emitted. The range of an alpha particle—up to 100 microns—is insufficient to cover the width of many tumors. However, radium-224's daughter atoms can diffuse up to 2–3 mm in the tissue, thus creating a "kill region" with enough radiation to potentially destroy an entire tumor, if the seeds are placed appropriately. Radium-224's half-life is short enough at 3.6 days to produce a rapid clinical effect while avoiding the risk of radiation damage due to overexposure. At the same time, the half-life is long enough to allow for handling and shipping the seeds to a cancer treatment center at any location across the globe.
Targeted alpha therapy for solid tumors involves attaching an alpha-particle-emitting radionuclide to a tumor-targeting molecule such as an antibody, that can be delivered by intravenous administration to a cancer patient.
Anti-alpha particle
Applications
Devices
Cancer treatment
Alpha radiation and DRAM errors
See also
Further reading
External links
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